Computational Design of Highly Potent Organic Superbases
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منابع مشابه
Rational design of a new class of polycyclic organic bases bearing two superbasic sites and their applications in the CO2 capture and activation process.
A new type of polycyclic organic superbases is reported with very high proton affinities in the gas phase and the pK(a) upto 45.8 units in acetonitrile. They have exhibited the 2nd pK(a) upto 44.4 units, which is the highest 2nd pK(a) reported till date. These organic superbases can be useful in the fixation of CO(2) released from different industrial sources.
متن کاملLiving Radical Polymerization via Organic Superbase Catalysis
Organic superbases reacted with alkyl iodides (R–I) to reversibly generate the corresponding alkyl radicals (R). Via this reaction, organic superbases were utilized as new and highly efficient organic catalysts in living radical polymerization. The superbase catalysts included guanidines, aminophosphines and phosphazenes. Low-polydispersity polymers (Mw/Mn = 1.1–1.4) were obtained up to high co...
متن کاملTuning Organic Carbon Dioxide Absorbents for Carbonation and Decarbonation
The reaction of carbon dioxide with a mixture of a superbase and alcohol affords a superbase alkylcarbonate salt via a process that can be reversed at elevated temperatures. To utilize the unique chemistry of superbases for carbon capture technology, it is essential to facilitate carbonation and decarbonation at desired temperatures in an easily controllable manner. Here, we demonstrate that th...
متن کاملKinetics screening of the N-alkylation of organic superbases using a continuous flow microfluidic device: basicity versus nucleophilicity.
We describe here the determination of the alkylation rate of a set of organic superbases by iodomethane in DMF using a microfluidic continuous flow reactor. Surprisingly, log k(Alkylation) follows the inverse trend of pK(BH+) of the base. Mayr's equation allows a more quantitative approach. From a synthetic point of view, TMGN and BEMP are demonstrated to be the best choices.
متن کاملSynthetic applications of polystyrene-supported 1,1,3,3-tetramethylguanidine.
Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparativ...
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تاریخ انتشار 2004